The mission of the Wellcome Sanger Institute is “To use information from genome sequences to advance understanding of biology and improve health.”
The Wellcome Sanger Institute is a world leading genomics research centre. We undertake large-scale research that forms the foundations of knowledge in biology and medicine. We are open and collaborative; we share our data, results, tools and technologies across the world to advance science. Our findings are used to improve health and to understand life on Earth.
Our science is large-scale and organised into Programmes, led by our Faculty who conceive and deliver our science, and supported by our Scientific Operations teams responsible for all data production pipelines at the Institute.
With secured funding from Wellcome Trust, we are able to strategically focus our work in five key research fields:
Parasites and Microbes: Investigates the common underpinning mechanisms of evolution, infection and resistance to therapy in bacteria and parasites. It also explores the genetics of host response to infection and the role of the microbiota in health and disease.
Tree of Life Investigates the diversity of complex organisms found in the UK through sequencing and cellular technologies. It also compares and contrasts species’ genome sequences to unlock evolutionary insights.
Cancer, Ageing and Somatic Mutation: Provides leadership in data aggregation and informatics innovation, develops high-throughput cellular models of cancer for genome-wide functional screens and drug testing, and explores somatic mutation’s role in clonal evolution, ageing and development.
Cellular Genetic:s Explores human gene function by studying the impact of genome variation on cell biology. Large-scale systematic screens are used to discover the impact of naturally-occurring and engineered genome mutations in human iPS cells, their differentiated derivatives, and other cell types.
Human Genetics: Applies genomics to population-scale studies to identify the causal variants and pathways involved in human disease and their effects on cell biology. It also models developmental disorders to explore which physical aspects might be reversible.
Life at Sanger Institute is unique. Set across 130 acres, just outside of Cambridge, our people are shaping the future by delivering life-changing science with the reach, scale, and creativity to solve some of humanity's greatest challenges. We have over 1,200 people, from 70+ nationalities. We know that the success of our institute depends on our people. We embrace everything that is unique about individuals and draw on their different perspectives.