Salary per annum £32,780-£41,093
Full Time or Part Time Full Time
Contract Type Fixed Term
Contract Length 3 years
Job Reference 84133
The Jones group are seeking a Postdoctoral Fellow to investigate gene networks that underpin the oncogenic mutants that colonise normal human tissues ( 1, 2, 3). You will have the opportunity to work at the leading edge of experimental functional genomics using whole genome CRISPR-based approaches to look at the dependencies of pre-cancer mutant genes in human cells and identify interventions to purge mutant clones from normal tissues and cut cancer risk.
The Jones lab are world-leaders in studying how oncogenic mutants spread through normal tissues in the earliest stages of cancer development. We combine expertise in sequencing, transgenic models, advanced 3D culture and Crispr screening to inform the development of novel interventions to prevent cancer. The Jones group pioneered identification of mutants in human tissues, understanding how the mutants change stem cell behaviour and have recently developed new 3D culture and Crispr methods. We work together as a supportive, multidisciplinary team of wet-lab experimental and data scientists to generate and analyse biological datasets including live imaging, single cell sequencing and whole genome screens to address the fundamental biological questions of how cancer develops.
You will have a PhD in cancer, functional genetics or cell biology, ideally with experience using CRISPR gene editing and running informatics packages. You will enjoy using innovative technologies to achieve your research goals and publish the results. You should have a proven track record of innovation and productivity, be a collaborative team player, have excellent organizational skills, and strong verbal and written communications skills.
When you join us as a Postdoctoral Fellow, you will benefit from a unique learning environment. We are proud to produce and analyse genetic and biological data on a scale unmatched by other institutes in Europe.
We pride ourselves in offering a first-class and well-resourced exceptional learning environment to equip you with the knowledge and skills you will need for a successful career in science.
Competencies and Behaviours:
For informal inquiries, please contact Phil Jones
Whilst the developments around COVID-19 continue to evolve, the Wellcome Genome Campus is closed for all but essential functions and facilities.
People remain at the centre of everything that we do and the majority of our staff are now working remotely to ensure continuity of operations, making use of remote communication and collaboration tools.
Interviews will be taking place virtually and the successful candidate should expect to be fully supported through remote on-boarding and working from home until the Campus re-opens to all staff. This approach may vary for individuals located overseas and/or where a visa is required and starting will be based on a number of factors, we will be able to provide specialist advice to those affected candidates.
We appreciate the importance of achieving a healthy work-life balance and support this with a number of benefits, including a flexible working policy for those who may wish to apply to amend their working pattern or arrangement. We welcome applications for this position that are looking for flexible working and equal consideration will be given to individuals regardless of their working preferences.
Please apply with your CV and a cover letter outlining your suitability for the role using the criteria set out above and in the job description.
Closing Date: 18th March 2021
The Wellcome Sanger Institute is a world leading genomics research centre. Our findings are used to improve health and to understand life on Earth.
There’s an attractive benefits package on offer at the Wellcome Genome Campus. We appreciate the importance of achieving work-life balance and support this with a number of family and carer-friendly policies. Plus a flexible working policy for those who may wish to amend their working pattern or arrangement.
As well as the usual benefits you would expect, we go much further:
Being part of the Wellcome Genome Campus you will be part of the beautiful working environment with an impressive range of benefits, services and facilities also including:
In 2020 we were awarded an Athena SWAN Silver Award. We will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.Continue reading
|Title||Postdoctoral Fellow - CRISPR|
|Employer||Wellcome Sanger Institute|
|Job location||Hinxton, CB10 1SA Cambridge|
|Published||February 19, 2021|
|Application deadline||March 18, 2021|
|Job types||Postdoc  |
|Fields||Biostatistics,   Cancer Research,   Molecular Biology,   Genetics,   Cell Biology  |