Abstract
The mechanisms that drive the migration and guidance of cell assemblies during embryonic development or cancer metastasis are diverse and remain poorly understood. Based on a perturbative approach, our project aims at investigating the dynamical migratory response of...
Abstract
Our project is on in-silico drug discovery: based on drug chemical synthesis, and thanks to the unprecedented molecular-level information enabled by ultrafast atomic force microscopy, we will use state-of-the-art mathematical algorithms to analyse visual data and set...
Abstract
Breathing is a continuous oscillatory activity, driven by a complex neuronal network deep in the brain. Core to this network are intermingled neuronal microcircuits that generate the respiratory rhythm, yet we still lack fundamental understanding about how it works...
Abstract
The reduced red blood cell (RBC) deformability in patients with sickle cell disease induces an increase in blood viscosity and leads to painful vaso-occlusive crises. RBC deformability influences their spatial organization under flow and the resulting rheology of...
Abstract
How cells determine their position and orientation (defined as a polar or nematic orientation of an intracellular polarity field) in a cell ensemble is a fundamental question in development. The model of positional information postulates the existence of a morphogen...
Abstract
Human induced pluripotent stem cells (hiPSCs), considered as in vitro equivalent of human epiblast, are a powerful model to study mechanisms underlying embryonic germ layer differentiation. Regulation of hiPSC fate change relies on dynamic interactions between...
KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to...
The Department of Biosciences and Nutrition performs research and education in several areas of medical science including aging, Alzheimer, bioorganic chemistry, biomaterial, molecular endocrinology, cancer biology, functional genomics, systems biology, epigenetics, structural...
The University of Gothenburg tackles society’s challenges with diverse knowledge. 53 500 students and 6 500 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around...
ERC-funded postdoctoral positions are available in the Dufrêne’s team to study staphylococcal adhesion and biofilm formation using atomic force microscopy (AFM). Staphylococcus aureus is a leading cause of hospital-acquired infections, which are often complicated by the...