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University of Nottingham

Research Associate / Fellow (Fixed Term)

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The Strategic Plan articulates the University's mission, vision and guiding principles.

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Reference SCI476821

Closing Date Tuesday, 30th November 2021

Job Type Research

Department Biosciences, Animal Sciences

Salary £27924 to £40927 per annum, (pro rata if applicable) depending on skills and experience (minimum £31406 with relevant PhD). Salary progression beyond this scale is subject to performance

Applications are invited for a Research Associate/Fellow to work on a BBSRC funded project investigating cell fate regulation during gastrulation in the laboratory of Prof Ramiro Alberio (University of Nottingham), in collaboration with Prof Jennifer Nichols (University of Cambridge) and Prof Matt Loose (University of Nottingham).

The project investigates the molecular mechanisms of gastrulation in mammals. The investigations will include working with embryos and in vitro models, such as gastruloids, and using single cell genomics as a mean to understand cellular trajectories during differentiation. This position will especially suit candidates with interest in single cell RNA seq., embryology and micromanipulation. The successful candidate will use in vitro functional assays to model developmental trajectories using embryonic stem cells, as well as gene editing of pig zygotes to create embryonic mutants. All the technologies required for the project are currently performed in our laboratory. This post offers a unique opportunity to work in fast developing fields (synthetic embryology, single cell genomics and gene editing) and to develop skills in state-of-the-art technologies.

Applicants must be highly motivated and self-driven, with a PhD (or close to completion) or equivalent in biology or related biological science. The successful candidate will have excellent laboratory skills including cell culture (e.g., 3D culture) and molecular biology; evidence of research methodologies and techniques including such as hybridization chain reaction; and experience using R/Ilastik/Fiji for image analysis (often based on machine-learning algorithms).

An ability to analyse and interpret data, evaluate and criticise texts and bring new insights; data handling skills (RNA seq. data, quantitative image analysis); and experience in growing embryonic stem cells (or organoids/gastruloids), and quantitative imaging techniques would be an advantage.

This is a full-time (36.25 hours), fixed term post for post to 31st December 2022. Arrangements for job share would be considered.

For more information on our lab activities please visit: http://www.nottingham.ac.uk/Biosciences/People/ramiro.alberio 

Informal enquiries may be addressed to Ramiro Alberio, email RAMIRO.ALBERIO@NOTTINGHAM.AC.UK. Please note that applications sent directly to this email address will not be accepted.

Our University has always been a supportive, inclusive, caring and positive community. We warmly welcome those of different cultures, ethnicities and beliefs – indeed this very diversity is vital to our success, it is fundamental to our values and enriches life on campus. We welcome applications from UK, Europe and from across the globe. For more information on the support we offer our international colleagues, see our Moving to Nottingham pages.

For successful international applicants, we provide financial support for your visa and the immigration health surcharge, plus an interest-free loan to help cover the cost of immigration-related expenses for any dependants accompanying you to the UK. For more information please see our webpage on Financial support for visas and the immigration health surcharge.

Job details

Title
Research Associate / Fellow (Fixed Term)
Location
University Park, United Kingdom
Published
2021-11-17
Application deadline
2021-11-30
Job type
Save as a favourite Create job alert

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The Strategic Plan articulates the University's mission, vision and guiding principles.

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