Your job alert was successfully created.
Ghent University
Postdoctoral Researcher - Department of Pediatrics and medical genetics
Ghent University
After decades of uninterrupted growth, Ghent University is one of the leading institutions of higher education and research in the Low Countries with 36,000 students and more than 8,000 staff members.
Visit employer page
JOB DETAILS
Published: 3 months ago
Application deadline: Aug 31
Location: Gent, Belgium
Please mention that you found this job on Academic Positions when applying.
SHARE THIS JOB

Postdoctoral Researcher - Department of Pediatrics and medical genetics

Last application date Aug 31, 2018 11:47
Department GE02 - Department of Pediatrics and medical genetics
Contract Limited duration
Occupancy rate 100%
Vacancy Type Research staff

Job description

The lab for Functional Genomics and Applied Bioinformatics at Ghent University is looking for a postdoctoral researcher to study the role of long non-coding RNAs in cancer.

Project background

The human genome is pervasively transcribed and produces thousands of non-coding RNA transcripts, the majority of which are so-called long non-coding RNAs (lncRNAs). LncRNA expression profiles can be highly tissue specific, making them attractive as candidate biomarkers or targets for therapy. While the exact function of most lncRNAs is still unknown, many were shown to play important roles in gene regulation and impact various cancer hallmarks. Our lab recently demonstrated that the melanoma-specific lncRNA SAMMSON is essential for melanoma cell survival and may serve as a novel therapeutic target for treatment of melanoma, underscoring the importance and relevance of lncRNA research.

The applicant will (help) establish new wet-lab technologies and methods to study lncRNA function in cancer including high-throughput CRISPR-interference, CRISPR library screens and various RNA pull-down strategies. The candidate will apply these methods to gain new insights in the function of lncRNAs and identify novel therapeutic targets in cancer.

Research lab

The research is embedded in a multi-disciplinary team of computational biologists and wet lab scientists, with access to state-of-the art facilities for sequencing, single cell analysis, tissue culture, animal modeling and high-performance computing. The research lab is part of the Center for Medical Genetics at Ghent University and the Cancer Research Institute Ghent.

Profile of the candidate

The applicant is expected to have a strong background in molecular biology. Experience with RNA pull-down, CRISPR, high-throughput screening technologies, xenografts or animal models is a plus. Excellent English writing and communication skills are mandatory. Experience in coaching students and technicians is a plus.

How to apply

Please send your CV with a motivation letter and contact details of a referent to Pieter.Mestdagh@UGent.be. Prof. Pieter Mestdagh Center for Medical Genetics (CMGG) Cancer Research Institute Ghent (CRIG) Ghent University De Pintelaan 185 9000 Ghent Belgium +32 9 332 5032

Continue reading
Apply now

APPLY FOR THIS JOB

Personal details
Upload your CV and attachments
The file format must be a .doc, .pdf, or .rtf, and the file cannot exceed 2 MB in size.
The file format must be a .doc, .pdf, or .rtf, and the file cannot exceed 2 MB in size.

By applying for a job listed on Academic Positions you agree to our terms and conditions and privacy policy.

SUBSCRIBE TO JOBS LIKE THIS

83 JOBS FROM THIS EMPLOYER

Ghent University
Ghent University
Location: Gent, Belgium | Closing on Aug 15
Research staff
Imagine a job advertisement that looks for flexible and dynamic employees. Would older job seekers feel as much attracted to this job as their younger counterparts? The Department of Personnel Management, Work, and Organizational Psychology has an exciting job opening for a...
Ghent University
Ghent University
Location: Gent, Belgium | Closing on Aug 20
Junior Assistant (PhD student) in environmental catalysis and technology
- You perform high-quality scientific research related to the application of seaweed-based activated carbon (AC) and biochar. The process parameters and the types of activation in the production of seaweed-based AC starting from the raw material will be investigated.
Ghent University
Ghent University
Location: Gent, Belgium | Closing on Aug 12
PhD student
The department of Public Health (Epidemiology and Prevention research unit) is looking for an enthusiastic PhD candidate to perform research on physical and psychosocial work demands in relation to cardiovascular and other health outcomes. The study includes advances objective...
Ghent University
Ghent University
Location: Gent, Belgium | Closing on Jul 31
Assistant (11666) - Electronics and information systems
Ghent University is a world of its own. Employing more than 8,000 people, it is actively involved in education and research, management and administration, and technical and social services on a daily basis. It is one of the largest, most exciting employers in the area and...